2012 Defensive Leaders
| Season | Stats |
| Rank | Player | Team | GP | Tkl | Ast | Total | Sack | Yds | PD | Int | Yds | TD | FF | FR | Yds | TD | Sfty |
| 1. | Adrian Wilson, S | NEP | 15 | 39 | 15 | 54 | 3 | 20 | 5 | 1 | -2 | 0 | 1 | 0 | 0 | 0 | 0 |
| 2. | Darryl Sharpton, LB | HOU | 7 | 15 | 12 | 27 | 0 | 0 | 2 | 1 | -2 | 0 | 0 | 1 | 0 | 0 | 0 |
| 3. | David Bruton, S | DEN | 6 | 2 | 0 | 2 | 0 | 0 | 1 | 1 | -2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4. | Jonathan Babineaux, DT | ATL | 15 | 25 | 6 | 31 | 3.5 | 16 | 5 | 1 | -2 | 0 | 1 | 1 | 15 | 1 | 0 |
| 5. | Justin Rogers, DB | BUF | 15 | 31 | 5 | 36 | 0 | 0 | 5 | 1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6. | DeAndre Levy, LB | DET | 14 | 55 | 25 | 80 | 0 | 0 | 3 | 1 | -1 | 0 | 0 | 1 | 0 | 0 | 0 |
| 7. | Ellis Lankster, CB | NYJ | 14 | 24 | 5 | 29 | 1 | 2 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 8. | Brad Jones, LB | GBP | 11 | 56 | 21 | 77 | 2 | 14 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 9. | Moise Fokou, LB | TEN | 14 | 27 | 11 | 38 | 1 | 6 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 10. | Jamarca Sanford, S | MIN | 15 | 47 | 14 | 61 | 0 | 0 | 5 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 |
| 11. | Julian Edelman, WR | NEP | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 22 | 1 | 0 |
| 12. | Reggie Walker, LB | ARI | 6 | 8 | 0 | 8 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13. | E.J. Biggers, CB | WAS | 13 | 39 | 9 | 48 | 1 | 8 | 7 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
| 14. | Pat McAfee, P | IND | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15. | Mike Rivera, LB | NEP | 5 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16. | Bryan Braman, LB | HOU | 11 | 3 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17. | D.J. Johnson, DB | DET | 5 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18. | Russell Allen, LB | JAX | 16 | 105 | 24 | 129 | 0.5 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19. | Dan Skuta, LB | SFO | 15 | 5 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20. | Steve McLendon, DT | PIT | 7 | 4 | 3 | 7 | 2 | 8 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 21. | Ashlee Palmer, LB | DET | 9 | 9 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22. | Al Afalava, S | TEN | 5 | 8 | 7 | 15 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23. | Sterling Moore, CB | DAL | 11 | 18 | 4 | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 14 | 0 | 0 |
| 24. | Jonathan Casillas, LB | TBB | 12 | 17 | 8 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 25. | Jason Williams, LB | CAR | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 26. | Orie Lemon, LB | KCC | 3 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 27. | Clay Matthews, LB | GBP | 12 | 32 | 11 | 43 | 13 | 84 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 28. | Aaron Curry, LB | NYG | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29. | Lawrence Sidbury, LB | IND | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 30. | Bront Bird, LB | SDC | 5 | 10 | 3 | 13 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 31. | Chris Owens, DB | CLE | 7 | 13 | 3 | 16 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 32. | Kaluka Maiava, LB | OAK | 15 | 30 | 18 | 48 | 2 | 10 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
| 33. | Tyrone McKenzie, LB | MIN | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34. | Victor Butler, LB | NOS | 12 | 20 | 3 | 23 | 3 | 25 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| 35. | Jarius Wynn, DE | SDC | 5 | 6 | 0 | 6 | 2 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 36. | Demarcus Dobbs, TE | SFO | 3 | 2 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 37. | Sealver Siliga, DT | DEN | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 38. | Vaughn Martin, DL | MIA | 9 | 12 | 7 | 19 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 39. | Henry Melton, DL | CHI | 13 | 31 | 12 | 43 | 6 | 50 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
| 40. | Jerraud Powers, CB | ARI | 8 | 33 | 7 | 40 | 0 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 41. | Matt Shaughnessy, DE | ARI | 13 | 25 | 6 | 31 | 3.5 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 42. | Mike Mitchell, S | CAR | 13 | 24 | 8 | 32 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 43. | Darcel McBath, S | SFO | 5 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 |
| 44. | O'Brien Schofield, LB | ARI | 7 | 26 | 8 | 34 | 4 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 45. | Rodger Saffold, T | STL | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 46. | Al Woods, DE | PIT | 3 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 47. | Dan Williams, DT | ARI | 13 | 33 | 11 | 44 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 48. | Torell Troup, DT | BUF | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 49. | Cam Thomas, DT | SDC | 12 | 14 | 7 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 50. | D'Anthony Smith, DT | JAX | 6 | 5 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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