2012 Defensive Leaders
| Season | Stats |
| Rank | Player | Team | GP | Tkl | Ast | Total | Sack | Yds | PD | Int | Yds | TD | FF | FR | Yds | TD | Sfty |
| 101. | Alfonzo Dennard, CB | NEP | 10 | 34 | 1 | 35 | 0 | 0 | 7 | 3 | 95 | 1 | 1 | 0 | 0 | 0 | 0 |
| 102. | E.J. Biggers, CB | WAS | 13 | 39 | 9 | 48 | 1 | 8 | 7 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
| 103. | Carlos Rogers, CB | SFO | 15 | 50 | 6 | 56 | 1 | 7 | 7 | 1 | 63 | 0 | 0 | 3 | 63 | 1 | 0 |
| 104. | Ryan Clark, FS | PIT | 15 | 74 | 28 | 102 | 0 | 0 | 7 | 2 | 26 | 0 | 2 | 1 | 2 | 0 | 0 |
| 105. | Josh Norman, CB | CAR | 15 | 50 | 21 | 71 | 0 | 0 | 7 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 106. | Isa Abdul-Quddus, S | NOS | 14 | 28 | 10 | 38 | 0 | 0 | 7 | 2 | 12 | 0 | 0 | 1 | 0 | 0 | 0 |
| 107. | Drayton Florence, DB | CAR | 7 | 21 | 4 | 25 | 0 | 0 | 7 | 1 | 29 | 0 | 0 | 0 | 0 | 0 | 0 |
| 108. | Brandon Spikes, LB | NEP | 14 | 56 | 35 | 91 | 1 | 2 | 7 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 |
| 109. | D'Qwell Jackson, LB | CLE | 16 | 63 | 51 | 114 | 3.5 | 5 | 7 | 2 | 31 | 1 | 2 | 2 | 0 | 0 | 0 |
| 110. | Brian Robison, DE | MIN | 15 | 26 | 11 | 37 | 8.5 | 42 | 7 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 0 |
| 111. | Perry Riley, LB | WAS | 16 | 70 | 55 | 125 | 3.5 | 24 | 7 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| 112. | Usama Young, S | OAK | 13 | 36 | 16 | 52 | 1.5 | 10 | 7 | 3 | 44 | 0 | 0 | 1 | 2 | 0 | 0 |
| 113. | Rahim Moore, S | DEN | 16 | 59 | 12 | 71 | 1 | 3 | 7 | 1 | 23 | 0 | 0 | 1 | 0 | 0 | 0 |
| 114. | Josh Thomas, CB | CAR | 13 | 21 | 7 | 28 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 |
| 115. | Kevin Williams, DT | MIN | 16 | 20 | 11 | 31 | 2 | 20 | 7 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 116. | Paul Posluszny, LB | JAX | 16 | 106 | 33 | 139 | 2 | 10 | 7 | 3 | 20 | 0 | 2 | 0 | 0 | 0 | 0 |
| 117. | Bernard Pollard, S | TEN | 13 | 71 | 27 | 98 | 2 | 14 | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 118. | Derrick Morgan, DE | TEN | 16 | 35 | 24 | 59 | 6.5 | 42 | 6 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| 119. | Brandon Browner, CB | SEA | 11 | 35 | 9 | 44 | 0 | 0 | 6 | 3 | 39 | 0 | 3 | 1 | 0 | 0 | 0 |
| 120. | Tracy Porter, CB | OAK | 5 | 16 | 5 | 21 | 0 | 0 | 6 | 1 | 43 | 1 | 0 | 0 | 0 | 0 | 0 |
| 121. | Mike Harris, CB | JAX | 13 | 43 | 4 | 47 | 1 | 11 | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 122. | Tavon Wilson, FS | NEP | 15 | 25 | 11 | 36 | 0 | 0 | 6 | 4 | 87 | 0 | 0 | 2 | 0 | 0 | 0 |
| 123. | Ahmad Brooks, LB | SFO | 16 | 35 | 12 | 47 | 6.5 | 50 | 6 | 1 | 50 | 1 | 2 | 0 | 0 | 0 | 0 |
| 124. | Russell Allen, LB | JAX | 16 | 105 | 24 | 129 | 0.5 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 125. | Jairus Byrd, S | BUF | 16 | 53 | 23 | 76 | 0 | 0 | 6 | 5 | 110 | 0 | 4 | 2 | 0 | 0 | 0 |
| 126. | William Gay, CB | PIT | 15 | 45 | 12 | 57 | 1 | 9 | 6 | 2 | 7 | 0 | 3 | 1 | 0 | 0 | 0 |
| 127. | Calais Campbell, DE | ARI | 13 | 50 | 13 | 63 | 6.5 | 28 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 128. | Chase Blackburn, LB | CAR | 15 | 61 | 33 | 94 | 3 | 19 | 6 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 |
| 129. | Ellis Lankster, CB | NYJ | 14 | 24 | 5 | 29 | 1 | 2 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 130. | Marcell Dareus, DT | BUF | 16 | 26 | 13 | 39 | 5.5 | 39 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 131. | Paul Kruger, LB | CLE | 15 | 30 | 12 | 42 | 9 | 47 | 6 | 1 | 0 | 0 | 1 | 1 | 9 | 0 | 0 |
| 132. | Barry Cofield, NT | WAS | 14 | 15 | 22 | 37 | 2.5 | 18 | 6 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 133. | D.J. Moore, CB | CAR | 11 | 25 | 5 | 30 | 0 | 0 | 6 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 134. | Charles Godfrey, S | CAR | 15 | 44 | 25 | 69 | 0 | 0 | 6 | 2 | 9 | 1 | 0 | 1 | 0 | 0 | 0 |
| 135. | Lardarius Webb, CB | BAL | 5 | 24 | 1 | 25 | 0 | 0 | 6 | 1 | 8 | 0 | 1 | 1 | 0 | 0 | 0 |
| 136. | Stephen Tulloch, LB | DET | 16 | 74 | 38 | 112 | 0.5 | 5 | 6 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 |
| 137. | NaVorro Bowman, LB | SFO | 16 | 93 | 51 | 144 | 2 | 9 | 6 | 1 | 11 | 0 | 1 | 0 | 0 | 0 | 0 |
| 138. | Wesley Woodyard, LB | DEN | 15 | 70 | 44 | 114 | 5.5 | 48 | 6 | 3 | 40 | 0 | 1 | 1 | 12 | 0 | 0 |
| 139. | Philip Wheeler, LB | MIA | 16 | 78 | 31 | 109 | 3 | 30 | 6 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 |
| 140. | Vince Wilfork, NT | NEP | 16 | 29 | 20 | 49 | 3 | 32 | 6 | 0 | 0 | 0 | 3 | 4 | 2 | 0 | 0 |
| 141. | Chykie Brown, CB | BAL | 14 | 12 | 2 | 14 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 142. | Jason Pierre-Paul, DE | NYG | 16 | 43 | 23 | 66 | 6.5 | 67 | 5 | 1 | 28 | 1 | 1 | 1 | 10 | 0 | 0 |
| 143. | Dimitri Patterson, CB | MIA | 9 | 30 | 3 | 33 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 144. | Ron Bartell, CB | DET | 7 | 20 | 7 | 27 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 145. | Nolan Carroll, CB | MIA | 13 | 41 | 6 | 47 | 1 | 5 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 146. | Donte Whitner, S | SFO | 16 | 61 | 21 | 82 | 0 | 0 | 5 | 1 | 42 | 1 | 2 | 1 | 0 | 0 | 0 |
| 147. | Orlando Scandrick, CB | DAL | 11 | 16 | 5 | 21 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 148. | Jeremy Mincey, DL | JAX | 16 | 35 | 6 | 41 | 3 | 19 | 5 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 |
| 149. | Tom Zbikowski, S | CHI | 11 | 27 | 11 | 38 | 1 | 6 | 5 | 1 | 20 | 0 | 0 | 0 | 0 | 0 | 0 |
| 150. | Morgan Burnett, S | GBP | 16 | 87 | 35 | 122 | 2 | 25 | 5 | 2 | 1 | 0 | 2 | 1 | 0 | 0 | 0 |
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