2012 Defensive Leaders
| Season | Stats |
| Rank | Player | Team | GP | Tkl | Ast | Total | Sack | Yds | PD | Int | Yds | TD | FF | FR | Yds | TD | Sfty |
| 1. | Victor Butler, LB | NOS | 12 | 20 | 3 | 23 | 3 | 25 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| 2. | Anthony Gaitor, DB | TBB | 4 | 6 | 1 | 7 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3. | Darcel McBath, S | SFO | 5 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 |
| 4. | Frank Kearse, DT | CAR | 6 | 8 | 5 | 13 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5. | Andrew Gachkar, LB | SDC | 8 | 12 | 3 | 15 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6. | Jimmy Wilson, CB | MIA | 13 | 28 | 7 | 35 | 2 | 14 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7. | David Ausberry, TE | OAK | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8. | Chris Owens, DB | CLE | 7 | 13 | 3 | 16 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 9. | Jacquian Williams, LB | NYG | 9 | 18 | 8 | 26 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10. | Lawrence Sidbury, LB | IND | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11. | Tyrone McKenzie, LB | MIN | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12. | Kaluka Maiava, LB | OAK | 15 | 30 | 18 | 48 | 2 | 10 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
| 13. | Jonathan Casillas, LB | TBB | 12 | 17 | 8 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 14. | Jason Williams, LB | CAR | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15. | Colin Jones, S | CAR | 10 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16. | Clay Matthews, LB | GBP | 12 | 32 | 11 | 43 | 13 | 84 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 17. | J.T. Thomas, LB | CHI | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18. | Aaron Curry, LB | NYG | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19. | Tommie Campbell, DB | TEN | 8 | 6 | 0 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20. | Cheta Ozougwu, DE | CHI | 1 | 3 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21. | Clinton McDonald, DT | SEA | 12 | 17 | 8 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22. | Sen'Derrick Marks, DT | JAX | 14 | 30 | 11 | 41 | 1.5 | 12 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 23. | Peria Jerry, DT | ATL | 10 | 11 | 3 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 24. | Ricky Jean-Francois, DT | IND | 8 | 12 | 10 | 22 | 2 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25. | Corvey Irvin, DT | CHI | 4 | 3 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 26. | Ziggy Hood, DE | PIT | 14 | 25 | 17 | 42 | 3 | 1 | 3 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 |
| 27. | Sammie Hill, DT | TEN | 10 | 9 | 6 | 15 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 28. | Roy Miller, DT | JAX | 12 | 15 | 8 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29. | Fili Moala, DE | IND | 5 | 2 | 12 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 30. | Vance Walker, DT | OAK | 15 | 21 | 11 | 32 | 3 | 20 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 31. | Ndamukong Suh, DT | DET | 15 | 25 | 10 | 35 | 8 | 67 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 32. | Jason Phillips, LB | PHI | 13 | 8 | 2 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 33. | Josh Mauga, LB | NYJ | 3 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34. | Rey Maualuga, LB | CIN | 16 | 62 | 60 | 122 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 35. | Jeff Tarpinian, LB | NEP | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 36. | Dannell Ellerbe, LB | MIA | 13 | 66 | 23 | 89 | 4.5 | 30 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 37. | Jasper Brinkley, LB | ARI | 16 | 62 | 35 | 97 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 |
| 38. | Jorvorskie Lane, FB | MIA | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39. | Ron Brace, DT | WAS | 2 | 2 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 40. | Mike Mitchell, S | CAR | 13 | 24 | 8 | 32 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 41. | Geno Atkins, DT | CIN | 15 | 39 | 15 | 54 | 12.5 | 90 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 |
| 42. | Desmond Bryant, DT | CLE | 14 | 24 | 12 | 36 | 3 | 19 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 43. | C.J. Spillman, FS | SFO | 10 | 3 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 44. | Chris Baker, NT | WAS | 10 | 8 | 8 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 45. | D.J. Johnson, DB | DET | 5 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 46. | Akeem Dent, LB | ATL | 15 | 40 | 21 | 61 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 47. | Russell Allen, LB | JAX | 16 | 105 | 24 | 129 | 0.5 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 48. | Michael Bennett, DE | SEA | 16 | 34 | 7 | 41 | 9 | 57 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 |
| 49. | Antonio Dixon, DT | PHI | 2 | 4 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 50. | Martez Wilson, LB | NOS | 12 | 9 | 4 | 13 | 3 | 18 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
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