2012 Defensive Leaders
| Season | Stats |
| Rank | Player | Team | GP | Tkl | Ast | Total | Sack | Yds | PD | Int | Yds | TD | FF | FR | Yds | TD | Sfty |
| 1. | Rob Ninkovich, DL | NEP | 15 | 32 | 26 | 58 | 8 | 51 | 1 | 0 | 0 | 0 | 5 | 4 | 3 | 0 | 0 |
| 2. | Vince Wilfork, NT | NEP | 16 | 29 | 20 | 49 | 3 | 32 | 6 | 0 | 0 | 0 | 3 | 4 | 2 | 0 | 0 |
| 3. | Julius Peppers, DE | CHI | 15 | 32 | 7 | 39 | 11.5 | 75 | 2 | 0 | 0 | 0 | 1 | 4 | 6 | 0 | 0 |
| 4. | Tim Dobbins, LB | HOU | 13 | 25 | 11 | 36 | 0 | 0 | 4 | 1 | 7 | 0 | 0 | 4 | 32 | 0 | 0 |
| 5. | Yeremiah Bell, S | ARI | 16 | 70 | 17 | 87 | 1 | 8 | 2 | 0 | 0 | 0 | 0 | 3 | 18 | 0 | 0 |
| 6. | Luke Kuechly, LB | CAR | 16 | 103 | 62 | 165 | 1 | 4 | 8 | 2 | 22 | 0 | 0 | 3 | 9 | 0 | 0 |
| 7. | Shaun Phillips, LB | DEN | 16 | 33 | 17 | 50 | 9.5 | 64 | 3 | 0 | 0 | 0 | 2 | 3 | 0 | 1 | 0 |
| 8. | Ed Reed, FS | HOU | 15 | 49 | 9 | 58 | 0 | 0 | 15 | 4 | 78 | 1 | 0 | 3 | 30 | 0 | 0 |
| 9. | Carlos Dunlap, DE | CIN | 14 | 34 | 7 | 41 | 6 | 55 | 3 | 1 | 14 | 1 | 4 | 3 | 2 | 0 | 0 |
| 10. | Kelvin Hayden, CB | CHI | 12 | 24 | 11 | 35 | 0 | 0 | 5 | 1 | 39 | 0 | 0 | 3 | 15 | 0 | 0 |
| 11. | C.J. Mosley, DL | DET | 15 | 36 | 9 | 45 | 2.5 | 27 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 |
| 12. | Carlos Rogers, CB | SFO | 15 | 50 | 6 | 56 | 1 | 7 | 7 | 1 | 63 | 0 | 0 | 3 | 63 | 1 | 0 |
| 13. | Quentin Jammer, DB | DEN | 16 | 55 | 9 | 64 | 0 | 0 | 9 | 3 | 89 | 1 | 1 | 3 | 0 | 1 | 0 |
| 14. | Wallace Gilberry, DE | CIN | 14 | 15 | 9 | 24 | 6.5 | 48 | 0 | 0 | 0 | 0 | 1 | 3 | 31 | 1 | 0 |
| 15. | Billy Winn, DL | CLE | 14 | 19 | 7 | 26 | 1 | 6 | 3 | 1 | 0 | 0 | 0 | 2 | 35 | 0 | 0 |
| 16. | Bryan Scott, S | BUF | 16 | 44 | 19 | 63 | 0 | 0 | 8 | 4 | 66 | 1 | 1 | 2 | 8 | 0 | 0 |
| 17. | Terence Newman, CB | CIN | 14 | 52 | 21 | 73 | 0 | 0 | 10 | 2 | 0 | 0 | 1 | 2 | 8 | 0 | 0 |
| 18. | Charles Tillman, CB | CHI | 15 | 73 | 12 | 85 | 0 | 0 | 16 | 3 | 71 | 3 | 10 | 2 | 0 | 0 | 0 |
| 19. | Robert McClain, CB | ATL | 14 | 48 | 7 | 55 | 0 | 0 | 10 | 1 | 32 | 0 | 0 | 2 | 28 | 0 | 0 |
| 20. | Curtis Lofton, LB | NOS | 16 | 82 | 41 | 123 | 1 | 12 | 7 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 |
| 21. | Tavon Wilson, FS | NEP | 15 | 25 | 11 | 36 | 0 | 0 | 6 | 4 | 87 | 0 | 0 | 2 | 0 | 0 | 0 |
| 22. | Joselio Hanson, CB | OAK | 15 | 48 | 12 | 60 | 0 | 0 | 5 | 2 | 24 | 0 | 1 | 2 | 1 | 0 | 0 |
| 23. | Frank Alexander, DE | CAR | 13 | 10 | 8 | 18 | 2.5 | 21 | 3 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 24. | Albert McClellan, LB | BAL | 14 | 29 | 13 | 42 | 1 | 11 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 25. | Cameron Jordan, DE | NOS | 16 | 40 | 26 | 66 | 8 | 54 | 3 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 0 |
| 26. | Kevin Williams, DT | MIN | 16 | 20 | 11 | 31 | 2 | 20 | 7 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 27. | Mario Williams, DE | BUF | 16 | 37 | 9 | 46 | 10.5 | 51 | 4 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 |
| 28. | Chad Greenway, LB | MIN | 16 | 96 | 50 | 146 | 3 | 14 | 4 | 1 | 3 | 0 | 0 | 2 | 0 | 0 | 0 |
| 29. | Craig Robertson, LB | CLE | 16 | 56 | 27 | 83 | 1 | 10 | 3 | 2 | 1 | 0 | 0 | 2 | 2 | 0 | 0 |
| 30. | D'Qwell Jackson, LB | CLE | 16 | 63 | 51 | 114 | 3.5 | 5 | 7 | 2 | 31 | 1 | 2 | 2 | 0 | 0 | 0 |
| 31. | Steve Gregory, S | NEP | 11 | 31 | 6 | 37 | 0 | 0 | 5 | 3 | 50 | 0 | 2 | 2 | 30 | 1 | 0 |
| 32. | Mike Adams, S | DEN | 16 | 60 | 20 | 80 | 1 | 2 | 12 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 |
| 33. | Josh Wilson, DB | WAS | 16 | 54 | 20 | 74 | 1 | 12 | 13 | 2 | 8 | 0 | 3 | 2 | 30 | 1 | 0 |
| 34. | Zach Brown, LB | TEN | 16 | 68 | 24 | 92 | 5.5 | 29 | 5 | 3 | 156 | 2 | 1 | 2 | 6 | 0 | 0 |
| 35. | Dont'a Hightower, LB | NEP | 14 | 43 | 17 | 60 | 4 | 21 | 3 | 0 | 0 | 0 | 0 | 2 | 6 | 1 | 0 |
| 36. | Courtney Upshaw, LB | BAL | 15 | 34 | 21 | 55 | 1.5 | 10 | 2 | 0 | 0 | 0 | 0 | 2 | 5 | 0 | 0 |
| 37. | Dashon Goldson, S | TBB | 16 | 53 | 14 | 67 | 0 | 0 | 10 | 3 | 21 | 0 | 1 | 2 | 71 | 0 | 0 |
| 38. | Antwan Barnes, LB | NYJ | 10 | 7 | 2 | 9 | 3 | 24 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0 |
| 39. | Mike Daniels, DE | GBP | 8 | 12 | 0 | 12 | 2 | 11 | 1 | 0 | 0 | 0 | 0 | 2 | 43 | 1 | 0 |
| 40. | J.J. Watt, DE | HOU | 16 | 69 | 12 | 81 | 20.5 | 139 | 16 | 0 | 0 | 0 | 4 | 2 | 7 | 0 | 0 |
| 41. | Stephen Tulloch, LB | DET | 16 | 74 | 38 | 112 | 0.5 | 5 | 6 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 |
| 42. | Jairus Byrd, S | BUF | 16 | 53 | 23 | 76 | 0 | 0 | 6 | 5 | 110 | 0 | 4 | 2 | 0 | 0 | 0 |
| 43. | Ziggy Hood, DE | PIT | 14 | 25 | 17 | 42 | 3 | 1 | 3 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 |
| 44. | Everson Griffen, DE | MIN | 12 | 20 | 3 | 23 | 8 | 77 | 2 | 1 | 29 | 1 | 0 | 2 | 5 | 0 | 0 |
| 45. | Jermaine Cunningham, LB | NEP | 12 | 16 | 8 | 24 | 2.5 | 21 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 46. | Reshad Jones, S | MIA | 16 | 74 | 21 | 95 | 1 | 5 | 9 | 4 | 28 | 0 | 2 | 2 | 24 | 0 | 0 |
| 47. | Morris Claiborne, CB | DAL | 15 | 43 | 12 | 55 | 0 | 0 | 8 | 1 | 0 | 0 | 1 | 2 | 50 | 1 | 0 |
| 48. | Linval Joseph, DT | NYG | 16 | 33 | 26 | 59 | 4 | 17 | 0 | 0 | 0 | 0 | 1 | 2 | 16 | 0 | 0 |
| 49. | Major Wright, S | CHI | 16 | 52 | 19 | 71 | 0 | 0 | 8 | 4 | 45 | 1 | 1 | 2 | 0 | 0 | 0 |
| 50. | Larry Foote, LB | PIT | 16 | 75 | 38 | 113 | 4 | 29 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 |
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